Antibody Engineering

Antibody Engineering

Antibody Engineering

Structure and sequence-based design and optimization of antibodies targeted to your antigen

Structure and sequence-based design and optimization of antibodies targeted to your antigen

Structure Prediction

Predict Immunoprotein Structures

  • Massively quick and scalable structure prediction for antibodies, TCRs, and nanobodies

  • Antibody-antigen complex structure prediction

Structure Prediction

Predict Immunoprotein Structures

  • Massively quick and scalable structure prediction for antibodies, TCRs, and nanobodies

  • Antibody-antigen complex structure prediction

Structure Prediction

Predict Immunoprotein Structures

  • Massively quick and scalable structure prediction for antibodies, TCRs, and nanobodies

  • Antibody-antigen complex structure prediction

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Design

Computationally design binders for your target

  • Generate de-novo mini protein and antibody binders for a given antigen
    structure

  • Redesign CDRs targeted to an antigen

  • Produce point mutations for increased binding affinity and stability

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Design

Build effortless. Customize superfast.

  • Generate de-novo mini protein and antibody binders for a given antigen
    structure

  • Redesign CDRs targeted to an antigen

  • Produce point mutations for increased binding affinity and stability

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Design

Computationally design binders for your target

  • Generate de-novo mini protein and antibody binders for a given antigen
    structure

  • Redesign CDRs targeted to an antigen

  • Produce point mutations for increased binding affinity and stability

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Optimize

Improve multiple protein therapeutic properties

  • Optimize sequences for thermostability, solubility, and other developability properties

  • Predict aggregation, immunogenicity, and developability for hundreds of thousands of sequences

  • Integrate experimental data for higher scoring accuracy over rounds of designs


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Optimize

Smooth look. Shiny creations.

  • Optimize sequences for thermostability, solubility, and other developability properties

  • Predict aggregation, immunogenicity, and developability for hundreds of thousands of sequences

  • Integrate experimental data for higher scoring accuracy over rounds of designs


Banner-3
Optimize

Improve multiple protein therapeutic properties

  • Optimize sequences for thermostability, solubility, and other developability properties

  • Predict aggregation, immunogenicity, and developability for hundreds of thousands of sequences

  • Integrate experimental data for higher scoring accuracy over rounds of designs


Docking

Dock protein-protein complexes at large scales

  • Predict binding poses of antibody-antigen complexes

  • Compute binding affinities using molecular dynamics and docking

Docking

Dock protein-protein complexes at large scales

  • Predict binding poses of antibody-antigen complexes

  • Compute binding affinities using molecular dynamics and docking

Docking

Dock protein-protein complexes at large scales

  • Predict binding poses of antibody-antigen complexes

  • Compute binding affinities using molecular dynamics and docking